BDBM257500 US9493441, 19-2
SMILES NC(=O)c1cn(nc1Nc1ccc2C(=O)NCc2c1)[C@@H](CC#N)C1CC1
InChI Key InChIKey=KKVUDCRZNXVINY-HNNXBMFYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 257500
TargetGlutathione S-transferase P/Tyrosine-protein kinase JAK2(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 105nMT: 2°CAssay Description:The ability of compounds to inhibit the activity of JAK1, JAK2, JAK3, and Tyk2 was measured using a recombinant purified GST-tagged catalytic domain ...More data for this Ligand-Target Pair